A City Guide To Changsha for This may affect the uptake of screening by some of those who would in fact have benefited from early detection and treatment. In the case of genetic testing, for example to identify whether an individual carries the gene that predisposes towards the development of Huntington’s disease an adult-onset disease, there is actually nothing that can be done to change the individual’s risk, and therefore some question the value of screening other than preparing the individual for their future. In contrast, some individuals, when identified as carrying the BRCA or BRCA gene for breast cancer, opt for prophylactic surgery i.e. breast removal in order that disease cannot manifest itself Kauff et al. Lerman et al. . A City Guide To Changsha 2016.